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Facile synthesis of functionalized spiro[indoline-3,2'-oxiran]-2-ones by Darzens reaction
A series of functionalized spiro[indoline-3,2'-oxiran]-2-ones was efficiently synthesized by Darzens reaction of phenacyl bromides with isatins both with N-alkyl groups and without N-substituent in the presence of potassium carbonate as a base catalyst. When two equivalents phenacyl bromides we...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Beilstein-Institut
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678858/ https://ncbi.nlm.nih.gov/pubmed/23766807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.105 |
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