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Azacytidine-induced reactivation of a DNA repair gene in Chinese hamster ovary cells.

Six X-ray-sensitive (xrs) strains of the CHO-K1 cell line were shown to revert at a very high frequency after treatment with 5-azacytidine. This suggested that there was a methylated xrs+ gene in these strains which was structurally intact, but not expressed. The xrs strains did not complement one a...

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Autors principals: Jeggo, P A, Holliday, R
Format: Artigo
Idioma:Inglês
Publicat: 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC367863/
https://ncbi.nlm.nih.gov/pubmed/2431295
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