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Azacytidine-induced reactivation of a DNA repair gene in Chinese hamster ovary cells.

Six X-ray-sensitive (xrs) strains of the CHO-K1 cell line were shown to revert at a very high frequency after treatment with 5-azacytidine. This suggested that there was a methylated xrs+ gene in these strains which was structurally intact, but not expressed. The xrs strains did not complement one a...

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Библиографические подробности
Опубликовано в::Mol Cell Biol
Главные авторы: Jeggo, P A, Holliday, R
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 1986
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Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367863/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2431295/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.8.2944-2949.1986
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