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Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production.

Retrovirus vectors can be made in the absence of helper virus by using retrovirus packaging cell lines. Helper-free virus is critical for a variety of gene transfer studies. The most useful packaging cell lines contain helper virus DNA from which the signal required for packaging of the viral RNA ge...

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Detalles Bibliográficos
Autores principales: Miller, A D, Buttimore, C
Formato: Artigo
Lenguaje:Inglês
Publicado: 1986
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC367857/
https://ncbi.nlm.nih.gov/pubmed/3785217
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