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Simple synthesis of pyrrolo[3,2-e]indole-1-carbonitriles

Alkylation of 5-nitroindol-4-ylacetonitriles with ethyl chloroacetate, α-halomethyl ketones, and chloroacetonitrile followed by a treatment of the products with chlorotrimethylsilane in the presence of DBU gives 1-cyanopyrrolo[3,2-e]indoles substituted in position 2 with electron-withdrawing groups....

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Detalhes bibliográficos
Main Authors: Trawczyński, Adam, Bujok, Robert, Wróbel, Zbigniew, Wojciechowski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678543/
https://ncbi.nlm.nih.gov/pubmed/23766809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.107
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