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Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells

Cell-based therapies for myelin disorders, such as multiple sclerosis and leukodystrophies, require technologies to generate functional oligodendrocyte progenitor cells. Here we describe direct conversion of mouse embryonic and lung fibroblasts to “induced” oligodendrocyte progenitor cells (iOPCs) u...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Najm, Fadi J., Lager, Angela M., Zaremba, Anita, Wyatt, Krysta, Caprariello, Andrew V., Factor, Daniel C., Karl, Robert T., Maeda, Tadao, Miller, Robert H., Tesar, Paul J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678540/
https://ncbi.nlm.nih.gov/pubmed/23584611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2561
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