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Control of transcription initiation in vitro requires binding of a transcription factor to the distal promoter of the ovalbumin gene.

We used a cell-free HeLa cell transcription system to identify and characterize transcription factors and the promoter elements that they recognize in RNA polymerase II-transcribed genes. Deletion of the region (-71 to -83) containing the GTCAAA direct repeat resulted in a marked decrease of specifi...

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Autori principali: Pastorcic, M, Wang, H, Elbrecht, A, Tsai, S Y, Tsai, M J, O'Malley, B W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1986
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC367845/
https://ncbi.nlm.nih.gov/pubmed/3785213
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