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Mechanical Stress and ATP Synthesis are coupled by Mitochondrial Oxidants in Articular Cartilage
Metabolic adaptation of articular cartilage under joint loading is evident and matrix synthesis seems to be critically tied to ATP. Chondrocytes utilize the glycolytic pathway for energy requirements but seem to require mitochondrial reactive oxygen species (ROS) to sustain ATP synthesis. The role o...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678272/ https://ncbi.nlm.nih.gov/pubmed/22930474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22223 |
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