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Increased Spironolactone in Advanced Heart Failure: Effect of Doses Greater than 25 mg/Day on Plasma Potassium Concentration

BACKGROUND: Daily doses of spironolactone higher than 25 mg are rarely used in heart failure (HF) patients, presumably due to the concern for hyperkalemia. However, in advanced HF, doses ≥50 mg have been found to be necessary to produce natriuresis. The aim of the present study was to examine the sa...

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Detalhes bibliográficos
Main Authors: Shchekochikhin, Dmitry, Lindenfeld, JoAnn, Schrier, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678142/
https://ncbi.nlm.nih.gov/pubmed/23801997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000346447
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