Intramolecular recombination between transfected repeated sequences in mammalian cells is nonconservative.

When plasmids carrying a fragmented gene with segments present as direct repeats are introduced into mammalian cells, recombination or gene conversion between the repeated sequences can reconstruct the gene. Intramolecular recombination leads to the deletion of the intervening sequences and the loss...

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Bibliographic Details
Main Authors: Chakrabarti, S, Seidman, M M
Format: Artigo
Language:Inglês
Published: 1986
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC367806/
https://ncbi.nlm.nih.gov/pubmed/3023937
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