The PEP4 gene encodes an aspartyl protease implicated in the posttranslational regulation of Saccharomyces cerevisiae vacuolar hydrolases.

pep4 mutants of Saccharomyces cerevisiae accumulate inactive precursors of vacuolar hydrolases. The PEP4 gene was isolated from a genomic DNA library by complementation of the pep4-3 mutation. Deletion analysis localized the complementing activity to a 1.5-kilobase pair EcoRI-XhoI restriction enzyme...

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Hauptverfasser: Woolford, C A, Daniels, L B, Park, F J, Jones, E W, Van Arsdell, J N, Innis, M A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC367804/
https://ncbi.nlm.nih.gov/pubmed/3537721
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