Effective Noninvasive Zygosity Determination by Maternal Plasma Target Region Sequencing

BACKGROUND: Currently very few noninvasive molecular genetic approaches are available to determine zygosity for twin pregnancies in clinical laboratories. This study aimed to develop a novel method to determine zygosity by using maternal plasma target region sequencing. METHODS: We constructed a sta...

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Hauptverfasser: Zheng, Jing, Xu, Chenming, Guo, Jing, Wei, Yuan, Ge, Huijuan, Li, Xuchao, Zhang, Chunlei, Jiang, Haojun, Pan, Ling, Tang, Weiping, Xie, Weiwei, Zhang, Hongyun, Zhao, Yangyu, Jiang, Fuman, Chen, Shengpei, Wang, Wei, Xu, Xun, Chen, Fang, Huang, Hefeng, Jiang, Hui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677919/
https://ncbi.nlm.nih.gov/pubmed/23762285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065050
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