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Noninvasive Assessment of Gene Transfer and Expression by In Vivo Functional and Morphologic Imaging in a Rabbit Tumor Model

PURPOSE: To evaluate the importance of morphology in quantifying expression after in vivo gene transfer and to compare gene expression after intra-arterial (IA) and intra-tumoral (IT) delivery of adenovirus expressing a SSTR2-based reporter gene in a large animal tumor model. MATERIALS AND METHODS:...

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Main Authors: Ravoori, Murali K., Han, Lin, Singh, Sheela P., Dixon, Katherine, Duggal, Jyoti, Liu, Ping, Uthamanthil, Rajesh, Gupta, Sanjay, Wright, Kenneth C., Kundra, Vikas
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677885/
https://ncbi.nlm.nih.gov/pubmed/23762226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062371
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