Propeptide-Mediated Inhibition of Cognate Gingipain Proteinases

Porphyromonas gingivalis is a major pathogen associated with chronic periodontitis. The organism’s cell-surface cysteine proteinases, the Arg-specific proteinases (RgpA, RgpB) and the Lys-specific proteinase (Kgp), which are known as gingipains have been implicated as major virulence factors. All th...

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Detalhes bibliográficos
Main Authors: Huq, N. Laila, Seers, Christine A., Toh, Elena C. Y., Dashper, Stuart G., Slakeski, Nada, Zhang, Lianyi, Ward, Brent R., Meuric, Vincent, Chen, Dina, Cross, Keith J., Reynolds, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677877/
https://ncbi.nlm.nih.gov/pubmed/23762374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065447
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