Hox and Pbx Factors Control Retinoic Acid Synthesis during Hindbrain Segmentation

In vertebrate embryos, retinoic acid (RA) synthesized in the mesoderm by Raldh2 emanates to the hind-brain neuroepithelium, where it induces anteroposterior (AP)-restricted Hox expression patterns and rhombomere segmentation. However, how appropriate spatiotemporal RA activity is generated in the hi...

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Bibliografiske detaljer
Main Authors: Vitobello, Antonio, Ferretti, Elisabetta, Lampe, Xavier, Vilain, Nathalie, Ducret, Sebastien, Ori, Michela, Spetz, Jean-François, Selleri, Licia, Rijli, Filippo M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677862/
https://ncbi.nlm.nih.gov/pubmed/21497760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.03.011
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