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A DNA fragment containing the upstream activator sequence determines nucleosome positioning of the transcriptionally repressed PHO5 gene of Saccharomyces cerevisiae.
The functional relationship of nucleosome positioning and gene expression is not known. Using high-copy plasmids, containing the yeast phosphate-repressible acid phosphatase gene (PHO5) and the TRP1/ARS1 vector system, I have determined the nucleosomal structure of the 5' region of the PHO5 gen...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1986
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC367782/ https://ncbi.nlm.nih.gov/pubmed/3023927 |
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