Stress-Induced Activation of the Dynorphin/κ-Opioid Receptor System in the Amygdala Potentiates Nicotine Conditioned Place Preference

Many smokers describe the anxiolytic and stress-reducing effects of nicotine, the primary addictive component of tobacco, as a principal motivation for continued drug use. Recent evidence suggests that activation of the stress circuits, including the dynorphin/κ-opioid receptor system, modulates the...

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Hauptverfasser: Smith, Jeffrey S., Schindler, Abigail G., Martinelli, Emma, Gustin, Richard M., Bruchas, Michael R., Chavkin, Charles
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677733/
https://ncbi.nlm.nih.gov/pubmed/22279233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2980-11.2012
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