Topotecan in patients with BRCA-associated and sporadic platinum-resistant ovarian, fallopian tube, and primary peritoneal cancers

OBJECTIVE: To evaluate the efficacy of topoisomerase I inhibitor, topotecan, in patients with recurrent BRCA+ versus BRCA− ovarian, fallopian tube, and primary peritoneal carcinomas. METHODS: A single-institution retrospective analysis of platinum-resistant patients characterized for the presence or...

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Autores principales: Hyman, David M., Zhou, Qin, Arnold, Angela G., Grisham, Rachel N., Iasonos, Alexia, Kauff, Noah D., Spriggs, David
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677700/
https://ncbi.nlm.nih.gov/pubmed/21855118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2011.07.019
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