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Genetic determinants of growth phase-dependent and adenovirus 5-responsive expression of the Chinese hamster thymidine kinase gene are contained within thymidine kinase mRNA sequences.

We have constructed a chimeric thymidine kinase (TK) minigene, pHe delta 6Ha, which combines the complete coding and 3' noncoding regions of a Chinese hamster TK cDNA with the promoter region and 5' untranslated region of the TK gene of herpes simplex virus type 1. We have transformed rat 4 cells to...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Lewis, J A, Matkovich, D A
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1986
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367769/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023925/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.6.2262-2266.1986
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