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Identification and Analysis of Occludin Phosphosites: A Combined Mass Spectrometry and Bioinformatics Approach

The molecular function of occludin, an integral membrane component of tight junctions, remains unclear. VEGF-induced phosphorylation sites were mapped on occludin by combining MS data analysis with bioinformatics. In vivo phosphorylation of Ser490 was validated and protein interaction studies combin...

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Autors principals: Sundstrom, Jeffrey M., Tash, Brian R., Murakami, Tomoaki, Flanagan, John M., Bewley, Maria C., Stanley, Bruce A., Gonsar, Kristin B., Antonetti, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677543/
https://ncbi.nlm.nih.gov/pubmed/19125584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr7007913
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