Viral DNA tethering domains complement replication-defective mutations in the p12 protein of MuLV Gag

The p12 protein of murine leukemia virus (MuLV) group-specific antigen (Gag) is associated with the preintegration complex, and mutants of p12 (PM14) show defects in nuclear entry or retention. Here we show that p12 proteins engineered to encode peptide sequences derived from known viral tethering p...

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Autori principali: Schneider, William M., Brzezinski, Jonathon D., Aiyer, Sriram, Malani, Nirav, Gyuricza, Mercedes, Bushman, Frederic D., Roth, Monica J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677494/
https://ncbi.nlm.nih.gov/pubmed/23661057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221736110
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