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Fundamental differences in endoreplication in mammals and Drosophila revealed by analysis of endocycling and endomitotic cells
Throughout the plant and animal kingdoms specific cell types become polyploid, increasing their DNA content to attain a large cell size. In mammals, megakaryocytes (MKs) become polyploid before fragmenting into platelets. The mammalian trophoblast giant cells (TGCs) exploit their size to form a barr...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3677442/ https://ncbi.nlm.nih.gov/pubmed/23613587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304889110 |
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