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Fundamental differences in endoreplication in mammals and Drosophila revealed by analysis of endocycling and endomitotic cells

Throughout the plant and animal kingdoms specific cell types become polyploid, increasing their DNA content to attain a large cell size. In mammals, megakaryocytes (MKs) become polyploid before fragmenting into platelets. The mammalian trophoblast giant cells (TGCs) exploit their size to form a barr...

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Detalhes bibliográficos
Main Authors: Sher, Noa, Von Stetina, Jessica R., Bell, George W., Matsuura, Shinobu, Ravid, Katya, Orr-Weaver, Terry L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677442/
https://ncbi.nlm.nih.gov/pubmed/23613587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304889110
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