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Nanoparticle-mediated Gene Silencing Confers Radioprotection to Salivary Glands In Vivo
Radiation treatment of head and neck cancers causes irreversible damage of the salivary glands (SG). Here, we introduce a preclinical mouse model for small-interfering RNA (siRNA)-based gene silencing to provide protection of SG from radiation-induced apoptosis. Novel, pH-responsive nanoparticles co...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3677305/ https://ncbi.nlm.nih.gov/pubmed/23511246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.42 |
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