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Nanoparticle-mediated Gene Silencing Confers Radioprotection to Salivary Glands In Vivo

Radiation treatment of head and neck cancers causes irreversible damage of the salivary glands (SG). Here, we introduce a preclinical mouse model for small-interfering RNA (siRNA)-based gene silencing to provide protection of SG from radiation-induced apoptosis. Novel, pH-responsive nanoparticles co...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Arany, Szilvia, Benoit, Danielle SW, Dewhurst, Stephen, Ovitt, Catherine E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677305/
https://ncbi.nlm.nih.gov/pubmed/23511246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.42
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