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Retrotransposon Ty1 RNA contains a 5′-terminal long-range pseudoknot required for efficient reverse transcription

Ty1 retrotransposon RNA has the potential to fold into a variety of distinct structures, mutation of which affects retrotransposition frequencies. We show here that one potential functional structure is located at the 5′ end of the genome and can assume a pseudoknot conformation. Chemoenzymatic prob...

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Hlavní autoři: Huang, Qing, Purzycka, Katarzyna J., Lusvarghi, Sabrina, Li, Donghui, LeGrice, Stuart F.J., Boeke, Jef D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677243/
https://ncbi.nlm.nih.gov/pubmed/23329695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.035535.112
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