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Irradiation to the young mouse brain caused long-term, progressive depletion of neurogenesis but did not disrupt the neurovascular niche

We investigated the effects of ionizing radiation on microvessel structure and complexity in the hippocampus. We also assessed neurogenesis and the neurovascular niche. Postnatal day 14 male C57BL/6 mice received a single dose of 8 Gy to the whole brain and were killed 6 hours, 1 week, 7 weeks, or 1...

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Main Authors: Boström, Martina, Kalm, Marie, Karlsson, Niklas, Hellström Erkenstam, Nina, Blomgren, Klas
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677115/
https://ncbi.nlm.nih.gov/pubmed/23486289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.34
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