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Sequences near the 3' secretion-specific polyadenylation site influence levels of secretion-specific and membrane-specific IgG2b mRNA in myeloma cells.

The expressed immunoglobulin gamma 2b (IgG2b) heavy-chain gene of 4T001 was cloned into the shuttle vector pSV2-gpt and transfected into myeloma J558L and lymphoma A20.2J. Northern blots indicated that the transfected gamma 2b gene was processed in a manner similar to the endogenous heavy chain in b...

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Dettagli Bibliografici
Autori principali: Kobrin, B J, Milcarek, C, Morrison, S L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1986
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC367696/
https://ncbi.nlm.nih.gov/pubmed/2878362
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