Cytochalasin releases mRNA from the cytoskeletal framework and inhibits protein synthesis.

Cytochalasin D was shown to be a reversible inhibitor of protein synthesis in HeLa cells. The inhibition was detectable at drug levels typically used to perturb cell structure and increased in a dose-dependent manner. The drug also released mRNA from the cytoskeletal framework in direct proportion t...

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Bibliographic Details
Main Authors: Ornelles, D A, Fey, E G, Penman, S
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC367692/
https://ncbi.nlm.nih.gov/pubmed/3785175
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