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Hepatitis C Virus Infection Activates a Novel Innate Pathway Involving IKKα in Lipogenesis and Viral Assembly

Hepatitis C virus interacts extensively with host factors not only to establish productive infection but also to trigger unique pathological processes. Our recent genome-wide siRNA screen demonstrated that IKKα is a critical host factor for HCV. Here we describe a novel NF-κB-independent and kinase-...

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Bibliografski detalji
Glavni autori: Li, Qisheng, Pène, Véronique, Krishnamurthy, Siddharth, Cha, Helen, Liang, T. Jake
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676727/
https://ncbi.nlm.nih.gov/pubmed/23708292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3190
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