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Biosynthesis of the v-sis gene product: signal sequence cleavage, glycosylation, and proteolytic processing.

The v-sis oncogene and its cellular homolog c-sis encode chain B of platelet-derived growth factor. Cells transformed by v-sis produce a platelet-derived growth factor-related molecule which is able to stimulate the platelet-derived growth factor receptor in an autocrine fashion. Site-directed mutag...

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Bibliografiske detaljer
Main Authors: Hannink, M, Donoghue, D J
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC367650/
https://ncbi.nlm.nih.gov/pubmed/3537701
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