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A human Ki-ras oncogene encodes two transforming p21 proteins.

The human Ki-ras gene was previously reported to contain two alternative fourth exons which encode two distinct p21 proteins differing only at their carboxy termini. The present study shows that either p21 protein is able on its own to transform NIH 3T3 cells to a tumorigenic state. IMAGES:

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Udgivet i:Mol Cell Biol
Principais autores: McCoy, M S, Weinberg, R A
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367646/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3537700/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.4.1326-1328.1986
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