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Hidden Markov Models for Evolution and Comparative Genomics Analysis

The problem of reconstruction of ancestral states given a phylogeny and data from extant species arises in a wide range of biological studies. The continuous-time Markov model for the discrete states evolution is generally used for the reconstruction of ancestral states. We modify this model to acco...

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Autors principals: Bykova, Nadezda A., Favorov, Alexander V., Mironov, Andrey A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676395/
https://ncbi.nlm.nih.gov/pubmed/23762278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065012
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