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Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals
The role of skeletal muscle in nonshivering thermogenesis (NST) is not well understood. Here we show that sarcolipin (Sln), a newly identified regulator of the sarco/endoplasmic reticulum Ca(2+)-ATPase (Serca) pump(1–5), is necessary for muscle-based thermogenesis. When challenged to acute cold (4 °...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3676351/ https://ncbi.nlm.nih.gov/pubmed/22961106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2897 |
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