Ulipristal Blocks Ovulation by Inhibiting Progesterone Receptor–Dependent Pathways Intrinsic to the Ovary

Ulipristal acetate (UPA), a progesterone receptor (PR) modulator, is used as an emergency contraceptive in women. Here, using a mouse model, we investigated the mechanism of action of UPA as an ovulation blocker. In mice, ovulation is induced ~12 hours following the treatment with exogenous gonadotr...

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Bibliografiske detaljer
Main Authors: Nallasamy, Shanmugasundaram, Kim, Jaeyeon, Sitruk-Ware, Regine, Bagchi, Milan, Bagchi, Indrani
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2013
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676258/
https://ncbi.nlm.nih.gov/pubmed/23012316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719112459239
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