Interleukin-22 Reduces Lung Inflammation during Influenza A Virus Infection and Protects against Secondary Bacterial Infection

Interleukin-22 (IL-22) has redundant, protective, or pathogenic functions during autoimmune, inflammatory, and infectious diseases. Here, we addressed the potential role of IL-22 in host defense and pathogenesis during lethal and sublethal respiratory H3N2 influenza A virus (IAV) infection. We show...

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Bibliografiske detaljer
Main Authors: Ivanov, Stoyan, Renneson, Joelle, Fontaine, Josette, Barthelemy, Adeline, Paget, Christophe, Fernandez, Elodie Macho, Blanc, Fany, De Trez, Carl, Van Maele, Laurye, Dumoutier, Laure, Huerre, Michel-René, Eberl, Gérard, Si-Tahar, Mustapha, Gosset, Pierre, Renauld, Jean Christophe, Sirard, Jean Claude, Faveeuw, Christelle, Trottein, François
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676141/
https://ncbi.nlm.nih.gov/pubmed/23596287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02943-12
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