Mucosal Immunization of Lactating Female Rhesus Monkeys with a Transmitted/Founder HIV-1 Envelope Induces Strong Env-Specific IgA Antibody Responses in Breast Milk

We previously demonstrated that vaccination of lactating rhesus monkeys with a DNA prime/vector boost strategy induces strong T-cell responses but limited envelope (Env)-specific humoral responses in breast milk. To improve vaccine-elicited antibody responses in milk, hormone-induced lactating rhesu...

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Detalhes bibliográficos
Main Authors: Fouda, Genevieve G. A., Amos, Joshua D., Wilks, Andrew B., Pollara, Justin, Ray, Caroline A., Chand, Anjali, Kunz, Erika L., Liebl, Brooke E., Whitaker, Kaylan, Carville, Angela, Smith, Shannon, Colvin, Lisa, Pickup, David J., Staats, Herman F., Overman, Glenn, Eutsey-Lloyd, Krissey, Parks, Robert, Chen, Haiyan, LaBranche, Celia, Barnett, Susan, Tomaras, Georgia D., Ferrari, Guido, Montefiori, David C., Liao, Hua-Xin, Letvin, Norman L., Haynes, Barton F., Permar, Sallie R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676124/
https://ncbi.nlm.nih.gov/pubmed/23596289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00528-13
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