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A Variant Macaque-Tropic Human Immunodeficiency Virus Type 1 Is Resistant to Alpha Interferon-Induced Restriction in Pig-Tailed Macaque CD4(+) T Cells

Human immunodeficiency virus type 1 (HIV-1) antagonizes innate restriction factors in order to infect and persistently replicate in a host. In a previous study, we demonstrated that HIV-1 NL4-3 with a simian immunodeficiency virus mne (SIVmne) vif gene substitution (HSIV-vif-NL4-3) could infect and...

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Detalhes bibliográficos
Main Authors: Thippeshappa, Rajesh, Ruan, Hongmei, Wang, Weiming, Zhou, Paul, Kimata, Jason T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676116/
https://ncbi.nlm.nih.gov/pubmed/23552412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00338-13
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