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Syndecan-1 Serves as the Major Receptor for Attachment of Hepatitis C Virus to the Surfaces of Hepatocytes

Our recent studies demonstrated that apolipoprotein E mediates cell attachment of hepatitis C virus (HCV) through interactions with the cell surface heparan sulfate (HS). HS is known to covalently attach to core proteins to form heparan sulfate proteoglycans (HSPGs) on the cell surface. The HSPG cor...

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Autors principals: Shi, Qing, Jiang, Jieyun, Luo, Guangxiang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676102/
https://ncbi.nlm.nih.gov/pubmed/23576506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03475-12
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