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Toscana Virus NSs Protein Inhibits the Induction of Type I Interferon by Interacting with RIG-I

Toscana virus (TOSV) is a phlebovirus, of the Bunyaviridae family, that is responsible for central nervous system (CNS) injury in humans. Previous data have shown that the TOSV NSs protein is a gamma interferon (IFN-β) antagonist when transiently overexpressed in mammalian cells, inhibiting IRF-3 in...

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Hlavní autoři: Gori-Savellini, Gianni, Valentini, Melissa, Cusi, Maria Grazia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676095/
https://ncbi.nlm.nih.gov/pubmed/23552410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03129-12
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