CDK9-Dependent Transcriptional Elongation in the Innate Interferon-Stimulated Gene Response to Respiratory Syncytial Virus Infection in Airway Epithelial Cells

Respiratory syncytial virus (RSV) is a negative-sense single-stranded RNA virus responsible for lower respiratory tract infections. During infection, the presence of double-stranded RNA (dsRNA) activates the interferon (IFN) regulatory factor 3 (IRF3) transcription factor, an event triggering expres...

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Detalhes bibliográficos
Main Authors: Tian, Bing, Zhao, Yingxin, Kalita, Mridul, Edeh, Chukwudi B., Paessler, Slobodan, Casola, Antonella, Teng, Michael N., Garofalo, Roberto P., Brasier, Allan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676079/
https://ncbi.nlm.nih.gov/pubmed/23596302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03399-12
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