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The Structure of the Herpes Simplex Virus DNA-Packaging Terminase pUL15 Nuclease Domain Suggests an Evolutionary Lineage among Eukaryotic and Prokaryotic Viruses

Herpes simplex virus 1 (HSV-1), the prototypic member of herpesviruses, employs a virally encoded molecular machine called terminase to package the viral double-stranded DNA (dsDNA) genome into a preformed protein shell. The terminase contains a large subunit that is thought to cleave concatemeric v...

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Main Authors: Selvarajan Sigamani, Sundaresan, Zhao, Haiyan, Kamau, Yvonne N., Baines, Joel D., Tang, Liang
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676077/
https://ncbi.nlm.nih.gov/pubmed/23596306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00311-13
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