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Characterization of the ospZ Promoter in Shigella flexneri and Its Regulation by VirB and H-NS

OspZ is an effector protein of the type III secretion system in Shigella spp. that downregulates the human inflammatory response during bacterial infection. The ospZ gene is located on the large virulence plasmid of Shigella. Many genes on this plasmid are transcriptionally repressed by the nucleoid...

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Main Authors: Basta, David W., Pew, Krystle L., Immak, Joy A., Park, Hiromichi S., Picker, Michael A., Wigley, Amanda F., Hensley, Christopher T., Pearson, Jaclyn S., Hartland, Elizabeth L., Wing, Helen J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676053/
https://ncbi.nlm.nih.gov/pubmed/23543709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00212-13
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