Crystal Structure and Site-Directed Mutagenesis Analyses of Haloalkane Dehalogenase LinB from Sphingobium sp. Strain MI1205

The enzymes LinB(UT) and LinB(MI) (LinB from Sphingobium japonicum UT26 and Sphingobium sp. MI1205, respectively) catalyze the hydrolytic dechlorination of β-hexachlorocyclohexane (β-HCH) and yield different products, 2,3,4,5,6-pentachlorocyclohexanol (PCHL) and 2,3,5,6-tetrachlorocyclohexane-1,4-di...

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Main Authors: Okai, Masahiko, Ohtsuka, Jun, Imai, Lica Fabiana, Mase, Tomoko, Moriuchi, Ryota, Tsuda, Masataka, Nagata, Koji, Nagata, Yuji, Tanokura, Masaru
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676048/
https://ncbi.nlm.nih.gov/pubmed/23564170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02020-12
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