Increased Resistance to Staphylococcus aureus Endophthalmitis in BALB/c Mice: Fas Ligand Is Required for Resolution of Inflammation but Not for Bacterial Clearance

FasL was recently shown be required for bacterial clearance in C57BL/6 mice that express the FasL.1 allotype. The FasL.2 allotype is expressed in BALB/c mice and exhibits increased binding affinity to and increased cytotoxic activity against Fas(+) target cells. Therefore, we hypothesized that BALB/...

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Bibliographic Details
Main Authors: Sugi, Norito, Whiston, Emily A., Ksander, Bruce R., Gregory, Meredith S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676017/
https://ncbi.nlm.nih.gov/pubmed/23569113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00405-12
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