Heterozygosity at the A625C Polymorphic Site of the MyD88 Gene Is Associated with Mycobacterium bovis Infection in Cattle

The study demonstrates that in cattle, animals heterozygous at the MyD88 A625C polymorphic marker have a 5-fold reduced risk for active pulmonary tuberculosis (odds ratio [OR] = 0.19; P = 6 × 10(−12)). The reduced risk, however, does not extend to animals with latent pulmonary tuberculosis (OR = 0.8...

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Hauptverfasser: Capparelli, Rosanna, De Chiara, Francesco, Nocerino, Nunzia, Medaglia, Chiara, Di Costanzo, Rosa, Ramunno, Luigi, Capuano, Federico, Casalinuovo, Francesco, Di Matteo, Antonio, Iannelli, Domenico
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Bacterial Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676007/
https://ncbi.nlm.nih.gov/pubmed/23545302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01398-12
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