Combinations of Monoclonal Antibodies to Anthrax Toxin Manifest New Properties in Neutralization Assays

Monoclonal antibodies (MAbs) are potential therapeutic agents against Bacillus anthracis toxins, since there is no current treatment to counteract the detrimental effects of toxemia. In hopes of isolating new protective MAbs to the toxin component lethal factor (LF), we used a strain of mice (C57BL/...

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Main Authors: Pohl, Mary Ann, Rivera, Johanna, Nakouzi, Antonio, Chow, Siu-Kei, Casadevall, Arturo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676002/
https://ncbi.nlm.nih.gov/pubmed/23509144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01328-12
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