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The assembly of a GTPase–kinase signalling complex by a bacterial catalytic scaffold

The fidelity and specificity of information flow within a cell is controlled by scaffolding proteins that assemble and link enzymes into signalling circuits(1,2). These circuits can be inhibited by bacterial effector proteins that post-translationally modify individual pathway components(3–6). Howev...

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Bibliographische Detailangaben
Hauptverfasser: Selyunin, Andrey S., Sutton, Sarah E., Weigele, Bethany A., Reddick, L. Evan, Orchard, Robert C., Bresson, Stefan M., Tomchick, Diana R., Alto, Neal M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675890/
https://ncbi.nlm.nih.gov/pubmed/21170023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09593
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