Quantitative Proteomics Reveals That the Specific Methyltransferases Txr1p and Ezl2p Differentially Affect the Mono-, Di- and Trimethylation States of Histone H3 Lysine 27 (H3K27)

Nuclear DNA in eukaryotic cells is assembled into the hierarchical chromatin structure via a process that is dynamically affected by the combinatorial set of post-translational modifications (PTMs) of histones in a dynamic manner responsive to physiological and environmental changes. The precise qua...

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Autores principales: Zhang, Chunchao, Molascon, Anthony J., Gao, Shan, Liu, Yifan, Andrews, Philip C.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2013
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675822/
https://ncbi.nlm.nih.gov/pubmed/23150054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.021733
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