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Modeling, Simulation, and Translation Framework for the Preclinical Development of Monoclonal Antibodies

The industry-wide biopharmaceutical (i.e., biologic, biotherapeutic) pipeline has been growing at an astonishing rate over the last decade with the proportion of approved new biological entities to new chemical entities on the rise. As biopharmaceuticals appear to be growing in complexity in terms o...

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Detalhes bibliográficos
Main Authors: Luu, Kenneth T., Kraynov, Eugenia, Kuang, Bing, Vicini, Paolo, Zhong, Wei-Zhu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675753/
https://ncbi.nlm.nih.gov/pubmed/23408094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9464-8
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