Platinum-Induced Ototoxicity in Children: A Consensus Review on Mechanisms, Predisposition, and Protection, Including a New International Society of Pediatric Oncology Boston Ototoxicity Scale

PURPOSE: The platinum chemotherapy agents cisplatin and carboplatin are widely used in the treatment of adult and pediatric cancers. Cisplatin causes hearing loss in at least 60% of pediatric patients. Reducing cisplatin and high-dose carboplatin ototoxicity without reducing efficacy is important. P...

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Autors principals: Brock, Penelope R., Knight, Kristin R., Freyer, David R., Campbell, Kathleen C.M., Steyger, Peter S., Blakley, Brian W., Rassekh, Shahrad R., Chang, Kay W., Fligor, Brian J., Rajput, Kaukab, Sullivan, Michael, Neuwelt, Edward A.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2012
Matèries:
Review Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675696/
https://ncbi.nlm.nih.gov/pubmed/22547603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.39.1110
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