Platinum-Induced Ototoxicity in Children: A Consensus Review on Mechanisms, Predisposition, and Protection, Including a New International Society of Pediatric Oncology Boston Ototoxicity Scale

PURPOSE: The platinum chemotherapy agents cisplatin and carboplatin are widely used in the treatment of adult and pediatric cancers. Cisplatin causes hearing loss in at least 60% of pediatric patients. Reducing cisplatin and high-dose carboplatin ototoxicity without reducing efficacy is important. P...

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Detalhes bibliográficos
Main Authors: Brock, Penelope R., Knight, Kristin R., Freyer, David R., Campbell, Kathleen C.M., Steyger, Peter S., Blakley, Brian W., Rassekh, Shahrad R., Chang, Kay W., Fligor, Brian J., Rajput, Kaukab, Sullivan, Michael, Neuwelt, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2012
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675696/
https://ncbi.nlm.nih.gov/pubmed/22547603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.39.1110
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