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Stabilization of the Conductive Conformation of a Voltage-gated K(+) (Kv) Channel: THE LID MECHANISM
Voltage-gated K(+) (Kv) channels are molecular switches that sense membrane potential and in response open to allow K(+) ions to diffuse out of the cell. In these proteins, sensor and pore belong to two distinct structural modules. We previously showed that the pore module alone is a robust yet dyna...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
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American Society for Biochemistry and Molecular Biology
2013
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3675597/ https://ncbi.nlm.nih.gov/pubmed/23609443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.468728 |
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