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Stabilization of the Conductive Conformation of a Voltage-gated K(+) (Kv) Channel: THE LID MECHANISM

Voltage-gated K(+) (Kv) channels are molecular switches that sense membrane potential and in response open to allow K(+) ions to diffuse out of the cell. In these proteins, sensor and pore belong to two distinct structural modules. We previously showed that the pore module alone is a robust yet dyna...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Santos, Jose S., Syeda, Ruhma, Montal, Mauricio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675597/
https://ncbi.nlm.nih.gov/pubmed/23609443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.468728
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