Increased Chemosensitivity via Targeting Testicular Nuclear Receptor 4 (TR4)-Oct4-Interleukin 1 Receptor Antagonist (IL1Ra) Axis in Prostate Cancer CD133(+) Stem/Progenitor Cells to Battle Prostate Cancer

Prostate cancer (PCa) stem/progenitor cells are known to have higher chemoresistance than non-stem/progenitor cells, but the underlying molecular mechanism remains unclear. We found the expression of testicular nuclear receptor 4 (TR4) is significantly higher in PCa CD133(+) stem/progenitor cells co...

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Bibliographic Details
Main Authors: Yang, Dong-Rong, Ding, Xian-Fan, Luo, Jie, Shan, Yu-Xi, Wang, Ronghao, Lin, Shin-Jen, Li, Gonghui, Huang, Chiung-Kuei, Zhu, Jin, Chen, Yuhchyau, Lee, Soo Ok, Chang, Chawnshang
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675583/
https://ncbi.nlm.nih.gov/pubmed/23609451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.448142
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